DNDi – Best science for the most neglected

Since 2003, the Drugs for Neglected Diseases initiative has developed 17 treatments for 6 deadly diseases, saving millions of lives.
We develop urgently needed treatments for neglected patients and work to ensure they’re affordable, available, and adapted to the communities who need them
We work hand in hand with partners in low- and middle-income countries to power our progress and strengthen innovation ecosystems that put people’s needs first
We speak out for policy change to enable more effective and equitable R&D and access to the fruits of science for all people in need, no matter their income or where they live
The European Medicines Agency has adopted a positive scientific opinion of acoziborole, a new treatment for T.b. gambiense sleeping sickness developed together with Sanofi and partners. Acoziborole is a testament to more than two decades of commitment from our partners and supporters who never stopped believing that the long and devastating history of sleeping sickness could be brought to a close.
We develop urgently needed treatments for neglected patients and ensure they’re affordable, available, and adapted to the communities who need them
Transmitted by the bite of a tsetse fly and causes severe neurological disorders
We delivered a revolutionary new drug to replace toxic treatments, and have ongoing trials to eliminate this disease
Causes heart and vital organ damage, after people are bitten by blood-sucking bugs
We delivered the first-ever treatment for children; now we’re searching for new drug candidates and working to boost access to care
Leaves disfiguring, life-long scars that lead to severe social stigma
We’re working to develop safer, shorter treatments for this disabling disease
Millions are left without treatment even though effective drugs exist
We’ve delivered a treatment as simple, safe, and effective as the best drugs available today – at a fraction of the cost
Is one of the world’s biggest parasitic killers, spread by the bites of sandflies
We’re working to develop a new generation of treatments to replace drugs that are painful, ineffective, and cause side effects
COVID-19 threw longstanding global health injustices into stark relief
We’re conducting research for new drugs before the next pandemic strikes and advocating for equitable innovation and access
Without treatment, deadly for thousands of people with advanced HIV
We’re working to improve access to life-saving treatments and developing an easier-to-use formulation
Cause debilitating illness, social exclusion, and long-term disability
We’re working across multiple diseases to develop missing cures that can prevent lasting harm
Rapidly spreading climate-sensitive disease with no specific treatment
We’re building a global partnership with dengue-endemic countries to develop a first treatment
Without treatment, half of children die before their second birthday
We’ve developed a strawberry-flavoured treatment to meet the needs of children long neglected by the global HIV response
Often ends in amputation​, after people get infected from stepping on a thorn
We conducted the world’s first trial for an alternative to current treatments, which are toxic and difficult to administer
We use the funds we receive to conduct life-saving research, build research networks, develop medicines, and advocate for neglected patients.
* 2025 financial year
Hideyo Noguchi Africa Prize
Princess of Asturias Award for International Cooperation
Prince Mahidol Award
Research!America Advocacy Award
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